Syllabus
This syllabus is for the Fall 2008 version of the course.
There are a maximum number of 100 points available. Points are derived
from the following set of activities.
| Activity Description |
Percentage of Grade |
| Homework |
20 |
| In-class Problems |
5 |
| In-class Presentation on current research article. Research
articles will be provided at least two weeks in advance of
presentations. |
5 |
|
Mid-Term exam (Closed book with student distilled notes allowed. Quantity of notes allowed to be determined.) |
30 |
| Final Exam (Closed book with student distilled notes allowed. Quantity of notes allowed to be determined.) |
40 |
| Who |
Contact Information |
| Michael R. Thompson (Instructor) |
mrt@case.edu |
| Timothy P. Eagan (Instructor) |
tpe2@case.edu |
| Robert W. Brown (Instructor) |
rwb@case.edu |
Regular office hours will be posted on the class website.
Will follow all university policies with respect to
basic conduct. All notes and homework solutions will be posted. Homework hints will
also be published on the www or via e-mail, depending upon time or
situation.
Magnetic Resonance Imaging: Physical Principles and Sequence Design
Haacke, Brown, Thompson, and Venkatesan
John Wiley and Sons
New York, NY 1999
ISBN: 0-471-35128-8
Amazon.com
Half.com
Please notice that when viewing class notes will go
into a regular html page, and leave the Physics web. If you
want to return to the main class page, best bet is to use a bookmark.
| August/September |
| Date |
Instructor |
Topic |
Resources |
| 08/25 |
Thompson/Eagan |
Course Briefing.
Introduction to MRI Lecture. Chapter 2:
Introduction to Classical Spin Physics. Why do forces and angular
momentums lead to rotating spins? |
|
| 09/01 |
Eagan |
Chapters 3 and 4: More Classical Spin Physics. |
|
| 09/08 |
Thompson |
Chapters 7 and 8:
Measuring the MR signal.
Introduction to how the MRI signal is measured, both conceptually and
practically. |
|
| 09/15 |
Thompson |
Chapters 9 and 10: MRI (Imaging that is).
Introduction to using the MR signal to make images. |
|
| 09/22 |
Eagan |
Chapters 11 and start 12: Review
properties of the Fourier transform as they impact on MRI. |
|
| 9/29 |
Eagan |
Chapter end 12 and 13: Review
properties of the Fourier transform as they impact on MRI. Identify how
to improve image quality by understanding the Fourier transform. |
|
| October |
| Date |
Instructor |
Topic |
Resources |
| 10/06 |
Thompson |
Chapter 15:
Signal, noise, and contrast in MRI. Very important stuff. |
|
| 10/13 |
Proctor TBD |
Mid-term Exam. |
|
| 10/20 |
Eagan |
Graduate classes don't stop for
fall break. Chapter 27: Review the
magnetics hardware that is associated
with an MRI scanner. Review all components of an MRI scanner. UHHS MRI site visit. (tentative) |
|
| 10/27 |
Eagan |
Chapters 5 and 6: Quantum Spin Physics. Analyze how
protons in one of two possible quantum states give rise to oscillating
magnetic fields that we measure, and are so consistent with classical
picture. Need this information to understand some MRI phenomenon.
Especially useful info for people looking into spectroscopy. |
You may bring one 8.5" by 11" sheet of paper with hand written notes on
it to the exam. You may right on both sides of the paper.
Exam will cover Chapters 1-13
|
| November |
| Date |
Instructor |
Topic |
Resources |
| 11/03 |
Thompson |
Chapters 18 and 19: Analyze fast imaging techniques. Important
to get as much information as possible during an MRI examination. Fast
imaging used for almost every clinical scan. |
|
| 11/10 |
Brown |
Parallel Imaging: Use
spatial information from multiple detectors to record more spatial
information per unit time. |
|
| 11/17 |
Thompson |
Chapters 23 and 24: Analyze the
impact of movement during data acquisition on MRI images. |
|
| 11/24 |
Thompson |
Diffusion Weighted
Imaging: Generation and use of contrast in MRI based upon the
microscopic Brownian motion of spins. |
|
| December |
| Date |
Instructor |
Topic |
Resources |
| 12/01 |
Students |
Present research papers in class. |
Each student is
required to review an MRI related article published in the last year,
and spend 5 minutes describing the paper to the class. Papers will be
assigned by the instructors at least 2 weeks in advance.
|
| 12/9 12:30-3:30 |
Final Exam |
Not Applicable |
Material from the entire semester will be covered.
|
Actually, will cover bulk of the text and you should be able to understand any topic
in the book on your own at the end of the class. If a consensus can be
reached by the class that something missed is more important than
something covered then the later part of the schedule may be modified.
Chapter 14 introduces projection reconstruction of images. However,
true projection reconstruction is rarely used in MRI today. If data is
collected using a rotating data technique it is usually interpolated
onto a cartesian grid and Fourier transformed. Will get MUCH more
information on projection reconstruction by taking a class focusing on
CT.
Chapter 16 adds a fair amount of detail to rf pulse design. Is very
important information, but must be dropped due to time constraints.
Chapter 22 concentrates on quantification of
rho,
T1, and
T2 which is a major topic in itself, but one that you should be
able to understand on your own after going through the course. Suffice
it to say that making quantitative measurements in MRI is difficult, and
is often very dependent on methodology which makes the results hard to
share/standardize.
Chapter 23 concentrates on magnetic properties of tissue, but also has
to be dropped due to time constraints.
Physics